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Those reactions are more concerning if they worsen, spread, become hot, drain fluid, or come with fever or systemic symptoms

More serious vitamin B12 side effects may include the following: Allergic reactions, such as hives, trouble breathing, or swelling of the face, lips, tongue or throat

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh

Hearing loss, worsening of tinnitus, and visual changes, as well as sensations of tingling, pinpricks, and pain have all been reported in patients undergoing electrical stimulation for tinnitus

Each temperature transition stresses the peptide structure