The results were quite impressive, showing a significant improvement in insulin sensitivity, a decrease in their levels of LDLs, often called the bad cholesterol, a lower BMI, and an increase in their levels of HDLs, often referred to as the good cholesterol (1)
In einer weiteren Versuchsreihe betrug die mittlere Bioverfgbarkeit des Peptids unter Verwendung der nasalen Formulierung 1 27,9% 9,7 und die mittlere Bioverfgbarkeit des Peptids unter Verwendung der nasalen Formulierung 2 34,7% 15,6, wobei in beiden Fllen die Bioverfgbarkeit mit derselben Menge des durch intravense Injektion verabreichten Peptids verglichen wurde
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Mice were housed in a controlled environment under a 12-h light/dark cycle and with ad libitum access to standard rodent chow and water
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