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Regardless of the source, the math remains the same

Phase 3 trials (SYNCHRONIZE-1 and SYNCHRONIZE-2) are currently underway and will provide the definitive comparison data

Values represent plasma insulin levels induced by glucose given orally (50 g/400 mL) (red circles) or an equivalent amount (isoglycemic) given intravenously (IV) (black circles)

Anyone experiencing significant cycle changes on semaglutide should tell their healthcare provider, who can help pinpoint whether the symptoms may be due to weight loss on semaglutide or a medical condition

The highest incidence occurs during the initial weeks of treatment and with each dose escalation